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Fluoro-Max™ Fluorescent Particulate Marker Particles - Green
Various dyes and particulate markers have been used to mark the “risk zone” in evaluating regional ischemia. Markers that have been used include Evans Blue, India Ink and Fluorescein; however, these dyes tend to rapidly migrate throughout the tissue making the risk zone difficult to identify. Fluorescent particulate markers are effective because they lodge in the capillaries and can be easily visualized under illumination.
The fluorescent marker beads are made of polymer containing a special fluorescent dye that excites effi ciently with a hand held UV lamp (Wood’s Lamp). The fluorescence is a brilliant yellow-green color. The particles are spherical, 1-10 micrometers in diameter, and have a density of 1.05 g/cm3. This makes them easy to suspend in an aqueous medium.
The particles are heavily loaded with dye, resulting in a very strong fluorescence that can easily be seen visually. They are invisible under white light, allowing the non-risk tissue to be examined for infarction. Since the dye is embedded in the interior of the particles, it does not leach out or cause indiscriminate staining.
- Marking the risk zone in myocardial infarction studies
- Firefli™ process creates highly stable, internally dyed microspheres
- Dye intensity uniformity
- Minimal photobleaching
- Excited and detected by a wide range of methods
- Particles can be observed directly in the matrix or media being tested
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