| PLA-Particles -M 자성입자 |
| Biodegradable particles |
- consist of magnetite (40% w/w) in a matrix of poly(D,L-lactic acid) with a molecular weight of 17.000 D
- available with mean diameters of 30 µm and 100 µm
- established in the field of magnetic drug targeting in connection with a controlled drug release (The half-life time of the beads under in-vivo conditions mainly depends on the molecular weight of the polymers and increases with the molecular weight of the polymer.)
- vailable with COOH or NH2 groups on the surface
- can be loaded with drugs on request
|
| Composition |
magnetic poly(lactic acid) particles |
| Surface |
plain, NH2, COOH |
| Solid content |
10 mg/ml |
| Quantity |
10 ml |
| Shape |
spherical |
| Density |
1.3 g/㎤ |
| Magnetization |
4.3 emu/g particles (H =1000 Oe) |
| Saturation Magnetization |
> 6.6 emu/g particles (H > 10.000 Oe) |
| Stable in |
aqueous buffers pH > 4 |
| Not stable in |
organic solvents, acidic solutions pH < 4 |
| Product Form |
aqueous suspension |
| Additional Remarks |
Storage at 2 - 8°C for 6 months |
